Explainer//6 min
GLP-1s and your period
Periods returning, periods changing character, periods arriving on a schedule for the first time in years. It is one of the most commonly reported effects in this drug class and one of the least documented.
Your Body
Mental Health
Mood, food noise, and the psychology of rapid change.
8 pieces
Explainer//6 min
Mood on a GLP-1
Regulators on two continents investigated whether these drugs cause suicidal thoughts and concluded they do not. That finding settles a narrow question and leaves a much larger one open.
Explainer//5 min
Sleep on a GLP-1
Most people sleep better on these drugs within a few months, for reasons that are entirely mechanical. A minority sleep considerably worse first, and almost nobody is warned about the interval.
Explainer//4 min
What a GLP-1 receptor agonist actually does
The mechanism is usually explained either in cartoon form or in a wall of pharmacology. Here is the version in between — enough to reason with, without pretending the picture is complete.
Deep Dive//5 min
Food noise
Nobody measured it, no trial listed it as an endpoint, and it is the single most common thing patients volunteer unprompted. The most consequential effect of these drugs may be one we have no instrument for.
Deep Dive//5 min
Year two on a GLP-1
Every article about these drugs ends at goal weight. That is roughly the midpoint. The second year is quieter, stranger, and the part where most of the decisions that matter actually get made.
Explainer//5 min
GLP-1s and alcohol
A striking number of people on these drugs report simply losing interest in alcohol. It was nobody's design goal, the mechanism is unresolved, and it may turn out to be one of the most consequential things this class does.
Deep Dive//4 min
Coming off a GLP-1
Regain after stopping is not a failure of willpower or a scandal about the drugs. It is what happens when you withdraw treatment for a chronic condition — and it is entirely predictable, which is why it should be discussed in month one, not month twenty.
Also in Your Body
On The Jab
The
GLP‑1
Handbook
Dr. Nick Robertson
MD
The book · 14 chapters
The GLP-1 Handbook
Everything I tell my own patients before their first injection. 214 pages of what actually matters in the first year — dosing, side effects, food, muscle, cost, and the part nobody prepares you for: maintenance.
$4Less than your morning coffee.
Priced at four dollars because it should be affordable to everyone taking these drugs — not because it's worth four dollars. No upsell, no course, no supplement line.