Skip to content

Independent GLP-1 journalism

On The JabDr. Nick Robertson, MD
On The Jab

The book · 14 chapters · 214 pages

The GLP-1 Handbook

Everything I tell my own patients before their first injection.

Written over eighteen months, from the questions patients actually asked — not the ones a marketing department wishes they would.

$4Less than your morning coffee.
  • PDF · EPUB · Kindle
  • Instant download
  • No subscription
  • No upsell

Why four dollars.

There is an entire industry charging two hundred dollars for a GLP-1 “protocol,” and a second industry giving the same information away in exchange for your email address and a referral commission on a compounding pharmacy.

This book is priced at four dollars because that is roughly what a coffee costs, and because a person spending a thousand dollars a month on medication should not then be asked to spend a fortune understanding it.

The revenue pays for hosting and the time it takes to read the trials properly. That is the whole business model. There is no course, no coaching program, no supplement line, and no affiliate link anywhere on this site.

Contents

  1. I

    Before the first injection

    What to settle with yourself, and with your clinician, in week zero.

  2. II

    How these drugs actually work

    Incretins, gastric emptying, and the brain — without the hand-waving.

  3. III

    Choosing a molecule

    Semaglutide, tirzepatide, and the honest case for each.

  4. IV

    The titration ladder

    Why going slower usually gets you further.

  5. V

    Nausea and the first eight weeks

    What is normal, what is not, and what to do at 2 a.m.

  6. VI

    Eating on a quiet appetite

    Protein floors, fiber, hydration, and the meals that still work.

  7. VII

    Protecting your muscle

    The single most under-discussed risk of rapid loss.

  8. VIII

    The red flags

    Gallbladder, pancreas, bowel, eyes — proportionate, not alarmist.

  9. IX

    Mood, food noise, and identity

    The psychological chapter nobody writes.

  10. X

    What it costs in America

    List price, coupons, coverage appeals, and the cash market.

  11. XI

    Compounded semaglutide

    How to think about the gray market without moralizing.

  12. XII

    Plateaus

    Why they happen and which ones are worth chasing.

  13. XIII

    Coming off

    Tapering, regain, and setting expectations honestly.

  14. XIV

    Maintenance, for years

    The part that begins when everyone else stops paying attention.

From Chapter V

Nausea and the first eight weeks

Almost everyone is told that nausea is common. Almost nobody is told what it feels like, when in the week it arrives, or how long they should tolerate it before picking up the phone.

Here is the shape of it in most people: a dull, low-grade fullness beginning twenty-four to forty-eight hours after the injection, worst on the day after a dose increase, and largely gone by the fourth or fifth day. It is not the nausea of food poisoning. It is the nausea of having eaten a very large meal an hour ago and being asked to eat another.

What matters clinically is not whether you feel sick. It is whether you can keep fluids down, and whether the sensation is accompanied by pain. Those two questions separate the ordinary from the urgent, and the rest of this chapter is about telling them apart.

214 pages · PDF, EPUB, Kindle

Not ready yet?

Take the newsletter instead. It's free, and it always will be.

One email each Sunday. Unsubscribe in a click. We never sell reader data.